Emeritus Professor Alan Seawright
Emeritus Professor
School of Veterinary Science
Publications
Book Chapters
Stewart, I., Seawright, A. A. and Shaw, G. R. (2008). Cyanobacterial poisoning in livestock, wild mammals and birds - an overview.. Cyanobacterial Harmful Algal Blooms: State of the Science and Research Needs. (pp. 613-637) edited by H. Kenneth Hudnell. New York, United States: Springer. doi: 10.1007/978-0-387-75865-7
Seawright, A. A. (2004). Pathological Aspects of Cyanobacterial Toxicity. Poisonous Plants and Related Toxins. (pp. 262-268) edited by T. Acamovic, C. S. Stewart and T. W. Pennycott. Wallingford, Oxon, UK: CABI Publishing.
Seawright, A. A., Ng, J. C., Oelrichs, P. B., Sani, Y., Nolan, C. C., Lister, A. T., Holton, J., Ray, D. E. and Osborne, R. (1999). Recent toxicity studies in animals using chemicals derived from cycads. Biology and conservation of cycads. (pp. 345-353) edited by C-J. Chen. Beijing: International Academic Publishers.
Journal Articles
Tinggi, Ujang, Sadler, Ross, Ng, Jack, Noller, Barry and Seawright, Alan (2016). Bioavailability study of arsenic and mercury in traditional Chinese medicines (TCM) using an animal model after a single dose exposure. Regulatory Toxicology and Pharmacology, 76, 51-56. doi: 10.1016/j.yrtph.2016.01.010
Stewart, Ian, Eaglesham, Geoffrey K., McGregor, Glenn B., Chong, Roger, Seawright, Alan A., Wickramasinghe, Wasantha A., Sadler, Ross, Hunt, Lindsay and Graham, Glenn (2012). First report of a toxic nodularia spumigena (Nostocales/Cyanobacteria) bloom in sub-tropical Australia. II. bioaccumulation of nodularin in isolated populations of mullet (Mugilidae). International Journal of Environmental Research and Public Health, 9 (7), 2412-2443. doi: 10.3390/ijerph9072412
Stewart, Ian, Carmichael, Wayne W., Sadler, Ross, McGregor, Glenn B., Reardon, Karen, Eaglesham, Geoffrey K., Wickramasinghe, Wasantha A., Seawright, Alan A. and Shaw, Glen R. (2009). Occupational and environmental hazard assessments for the isolation, purification and toxicity testing of cyanobacterial toxins. Environmental Health, 8 (52), 1-12. doi: 10.1186/1476-069X-8-52
Osborne, Nick, Seawright, Alan and Shaw, Glen (2008). Dermal toxicology of Lyngbya majuscula, from Moreton Bay, Queensland, Australia. Harmful Algae, 7 (5), 584-589. doi: 10.1016/j.hal.2007.12.022
Stewart, Ian, Seawright, Alan A., Schluter, Philip J. and Shaw, Glen R. (2006). Primary irritant and delayed-contact hypersensitivity reactions to the freshwater cyanobacterium Cylindrospermopsis raciborskii and its associated toxin cylindrospermopsin. B M C Dermatology, 6 (5) 5, 1-12. doi: 10.1186/1471-5945-6-5
Krishnamohan, K., Seawright, A. A. and Ng, J. C. (2006). Monomethylarsonous acid MMAIII is carcinogenic in mice. The Toxicologist, 90 (1), 427.
Butt, Alison J., Roberts, Caroline G., Seavvright, Alan A., Oelrichs, Peter B., MacLeod, John K., Liaw, Tracy Y.E., Kavallaris, Maria, Somers-Edgar, Tiffany J., Lehrbach, Gillian M., Watts, Colin K. and Sutherland, Robert L. (2006). A novel plant toxin, persin, with in vivo activity in the mammary gland, induces Bim-dependent apoptosis in human breast cancer cells. Molecular Cancer Therapeutics, 5 (9), 2300-2309. doi: 10.1158/1535-7163.MCT-06-0170
Senogles-Derham, P.-J., Seawright, A., Shaw, G., Wickramasinghe, W. and Shahin, M. (2003). Toxicological aspects of treatment to remove cyanobacterial toxins from drinking water determined using the heterozygous P53 transgenic mouse model. Toxicon, 41 (8), 979-988. doi: 10.1016/S0041-0101(03)00070-9
Chong, M. W. K., Wong, B. S. F., Lam, P. K. S., Shaw, G. R. and Seawright, A. A. (2002). Toxicity and uptake mechanism of cylindrospermopsin and lophyrotomin in primary rat hepatocytes. Toxicon, 40 (2), 205-211. doi: 10.1016/S0041-0101(01)00228-8
Seawright, A. A., Norris, R. L., Shaw, G. R., Moore, M. and Burgess, V. (2000). Toxicity of the Cyanobacterial Toxin, Cylindrospermopsin in Mammals. Toxicology, 148 (1), 75-76.
Norris, R. L., Seawright, A. A., Shaw, G. R. and Moore, M. (2000). The metabolism, distribution and excretion of the cyanobacterial hepatotoxin cylindrospermopsin. Toxicology Letters, 116 (1/116), 48-48.
Prakash, A. S., Pereira, T. N., Reilly, P. E. B. and Seawright, A. A. (1999). Pyrrolizidine alkaloids in human diet. Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 443 (1&2), 53-67. doi: 10.1016/S1383-5742(99)00010-1
Osborne, Roy, Grove, Andrew, Oh, Peter, Mabry, Tom J., Ng, Jack C. and Seawright, Alan A. (1994). The magical and medicinal usage of Stangeria eriopus in South Africa. Journal of Ethnopharmacology, 43 (2), 67-72. doi: 10.1016/0378-8741(94)90005-1
Auer, D. E., Ng, J. C. and Seawright, A. A. (1993). Free radical oxidation products in plasma and synovial fluid of horses with synovial inflammation. Australian Veterinary Journal, 70 (2), 49-52. doi: 10.1111/j.1751-0813.1993.tb15137.x
Small, A. C., Kelly, W. R., Seawright, A. A., Mattocks, A. R. and Jukes, R. (1993). Pyrrolizidine alkaloidosis in a two month old foal. Zentralblatt fur Veterinarmedizin. Reihe A, 40 (3), 213-218. doi: 10.1111/j.1439-0442.1993.tb00619.x
Mills, P. C., Ng, J. C., Seawright, A. A. and Auer, D. E. (1993). Vascular leakage induced by histamine, bradykinin, serotonin and prostaglandin E2 in greyhounds. Australian Veterinary Journal, 70 (1), 21-24. doi: 10.1111/j.1751-0813.1993.tb00791.x
Auer, D. E., Ng, J. C., Reilly, J. S. and Seawright, A. A. (1991). Anti-inflammatory drugs inhibit degradation of equine synovial fluid induced by free radicals. Australian Veterinary Journal, 68 (12), 403-405. doi: 10.1111/j.1751-0813.1991.tb03112.x
Auer, D. E., Ng, J. C. and Seawright, A. A. (1989). A suspected case of acute copper toxicity in a horse. Australian Veterinary Journal, 66 (6), 191-192. doi: 10.1111/j.1751-0813.1989.tb09803.x
Auer, D. E., Ng, J. C., Hrdlicka, J. and Seawright, A. A. (1989). The elimination of injected superoxide dismutase from synovial fluid of the horse. Australian Veterinary Journal, 66 (4), 117-119. doi: 10.1111/j.1751-0813.1989.tb09763.x
Pass M.A. and Seawright A.A. (1982). Effect of amitraz on contractions of the guinea-pig ileum in vitro. Comparative Biochemistry and Physiology. Part C, Comparative, 73 (2), 419-422. doi: 10.1016/0306-4492(82)90146-0
Roberts, M.C. and Seawright, A.A. (1978). The effects of prolonged daily low level mercuric chloride dosing in a horse. Veterinary and Human Toxicology, 20 (6), 410-415.
Pass M.A., Seawright A.A. and Heath T. (1976). Effect of ingestion of Lantana camara L. on bile formation in sheep. Biochemical Pharmacology, 25 (18), 2101-2102. doi: 10.1016/0006-2952(76)90438-X
Conference Papers
Krishnamohan, M., Seawright, A. A., Moore, M. R. and Ng, J. C. (2010). Carcinogenesis in female C57Bl/6J mice chronically exposed to sodium arsenate (Asv) in drinking water for 2 years. 3rd International Conference on Environmental Toxicology, Environmental Toxicology 2010, Limassol, Cyprus, 4-6 May 2010. Southampton, Hants, United Kingdom: W I T Press. doi: 10.2495/ETOX100021
Krishnamohan, M., Seawright, A. A., Kiupel, M. and Ng, J. C. (2007). P06: Monomethyl arsonous acid (MMA''') causes haematologic malignancies in C57Bl/6J female mice. 5th European Congress of Toxicologic Pathology and 6th International Congress of the IFSTP, Basel, Switzerland, 16 - 19 September, 2007. not found: European Society of Toxicologic Pathology.
Krishnamohan, M., Seawright, A. A., Moore, M. R., Lam, P. and Ng, J. C. (2005). Is Monomethyhlarsonous Acid (MMA111) A Carcinogen?. 5th Annual Health and Medical Research Conference of Queensland, Brisbane, Queensland, 3-4 November 2005. Brisbane, Queensland: Queensland Health.
Krishnamohan, M., Seawright, A. A., Moore, M. R. and Ng, J. C. (2005). Dose-Response Relationship for Cancer End Point Induced by Arsenic in a Mouse Model. Science Week at QHSS 2005, Brisbane, Queensland, 15-19 August 2005. Brisbane, Queensland: EnTox, The University of Queensland.
Krishnamohan, M., Seawright, A. A., Moore, M. R., Lam, P. and Ng, J. C. (2005). Cancer end point induced by arsenic in a mouse model. 5th Annual Health and Medical Research Conference of Queensland, Brisbane, Queensland, 3-4 November 2005. Brisbane, Queensland: Queensland Health.
Tinggi, U., Cooper, K., Noller, B. N., Sadler, R., Connell, D., Golding, G. M., Ng, J. C., Seawright, A. A. and Yu, J. (2005). A study of the variation in levels of toxic elements in chinese herbal medicines and their bioaccessibility. 5th Annual Health and Medical Research Conference of Queensland, Brisbane, Queensland, 3-4 November 2005. Brisbane, Queensland: Queensland Health.
Shen, X., Seawright, A. A., Shaw, G. R., Satarug, S., Stewart, I., Wickramasinghe, W. A., Eaglesham, G., Lam, P. and Moore, M.R. (2004). Dermal Toxicity of cylindrospermopsin in balb/C mice. XIth International Conference on Harmful Algae, Cape Town, South Africa, 14-19 November, 2004. Amsterdam ; New York: Elsevier Science.
Shaw, Glen R., McKenzie, Ross A., Wickramasinghe, Wasa A., Seawright, Alan A., Eaglesham, Geoff K. and Moore, Michael R. (2004). Comparative toxicity of the cyanobacterial toxin cylindrospermopsin between mice and cattle: Human implications. Xth International Conference on Harmful Algae, St. Pete Beach, Florida, U.S.A, 21-25 October 2002. Florida, U.S.A.: Florida Fish and Wildlife Conservation Commission, Florida Institute of Oceanography, and Intergovernmental Oceanographic Commission of UNESCO.
Shaw, G. R., Seawright, A. A., Wickramasinghe, W. A. and Moore, M. R. (2003). Health Aspects of cyanobacterial toxins in drinking water. Specialty Conference: Chemicals of Concern in Water, Sydney, 4-5 June 2003. Artarmon NSW: Australian Water Association.
Seawright, A. A. (2002). Pathological changes in the mammary gland of the lactating mouse caused by the avocado antifungal toxin. 18th Panamerican Congress of Veterinary Sciences, Havana, Cuba, 18-22 November 2002. Havana, Cuba: Artes Graficas.
Seawright, A. A. (2002). The toxicity of Argeratina Adenophora. 18th Panamerican Congress of Veterinary Sciences, Havana, Cuba, 18-22 November 2002. Havana, Cuba: Artes Graficas.
Seawright, A. A. (2002). Tissue pyrrolic metabolites in the diagnosis of pyrrolizidinosis. 18th Panamerican Congress of Veterinary Sciences, Havana, Cuba, 18-22 November 2002. Havana, Cuba: Artes Graficas.
Seawright, A. A. (2002). Hepatotoxicity in cattle using drinking water infested with the cyanobacterium cylindrospermopsis raciborskii. 18th Panamerican Congress of Veterinary Sciences, Havana, Cuba, 18-22 November 2002. Havana, Cuba: Artes Graficas.
Burgess, V., Seawright, A. A., Shaw, G. R. and Moore, M. (2001). Acute oral toxicity of pectlnotoxin-2 Seco acid and 7 epi-pectl-notoxin-2 Seco acid in mice. IXth International Congress of Toxicology, Brisbane, 8-12 July, 2001. Ireland: Elsevier Science Ireland Ltd.
Norris, R. L., Seawright, A. A., Shaw, G. R. and Moore, M. (2001). Inter-individual variability in response of mice to cylindrospermopsin. IXth International Congress of Toxicology, Brisbane, 8-12 July, 2001. Ireland: Elsevier Science Ireland Ltd.
Oelrichs, P. B., MacLeod, J., Seawright, A. A. and Moore, M. (2000). Isolation and identification of the toxic peptides lophyrotomin and pergidin from Lophyrotoma zonalis (Pergidae) sawfly larvae. EUROTOX 2000 (Association of European Toxicologists), London, England, 17-20 September 2000. Amsterdam, Netherlands: Elsevier Science. doi: 10.1016/S0378-4274(00)80001-6
Shaw, G. R., Seawright, A. A., Shahin, M., Senogles, P., Mueller, J. and Moore, M. (2000). The Cyanobacterial toxin, cylindrospermopsin: Human Health Risk Assessment. 9th Intern Conf on Harmful Algal Blooms, Hobart, 7-11 February 2000. Hobart: University of Tasmania.
Seawright, A. A. (2000). The Toxic Effects of Some of the Ingredients of Plants of Possible Use as Medicinal Herbs. 10th Asian Symp. on Medic Plants, Spices & Other Natural Prod, Dhaka, Bangladesh, 18-23 November 2000. Dhaka, Bangladesh: ASOMPSX.
Shahin, M., Seawright, A. A., Smith, B. L. and Prakash, A. S. (2000). Molecular Mechanism of Bracken Carcinogenesis. 1st International Workshop Plants Toxicity for Animals & Humans, Havana, Cuba, 10-12 May 2000. Havana, Cuba: Centro Nacional de Sanidad Agropecuaria (CENSA).
Shaw, G. R., Seawright, A. A. and Moore, M. (2000). Toxicology and human health implications of the cyanobacterial toxin, cylindrospermopsin. X Intern IUPAC Symp on Mycotoxins and Phycotoxins, Guaruja, Brazil, 21-25 May 2000. Sal Paulo, Brazil: Instituto Adolfo Lutz.
Seawright, A. A. (1999). Pathological aspects of cyanobacterial toxicity in Australia. Australian Society for Veterinary Pathology Annual Conference, University of Melbourne, 15-16 May 1999. melbourne: University of Melbourne.
Shahin, M., Seawright, A. A., Smith, B. L. and Prakash, A. S. (1999). Bracken carcinogenesis. Pan-African Environmental Mutagen Society. PAEMS '99 - 3rd International Conference, Harare, Zimbabwe, 1-5 March 1999. Harare, Zimbabwe, Africa: Pan-African Environmental Mutagen Society.
Shahin, M., Seawright, A. A., Smith, B. L. and Prakash, A. S. (1999). Molecular mechanisms of bracken carcinogenesis. Bracken fern : toxicity, biology and control ; contributions to an international conference, Manchester, UK, 20-23 July 1999. Manchester, UK: University of Manchester.
Shaw, G. R., Seawright, A. A. and Moore, M. (1999). Cylindrospermopsin, A cyanobacterial alkaloid toxin - Evaluation of its pharmacological activity. 6th International Congress of Therapeutic Drug Monitoring & Clinical Toxicology, Cairns, 13-17 September 1999. Cairns: Int. Assoc. of Therapeutic Drug Monitoring & Clinical Toxicology.
Ng, J. C., Seawright, A. A., Qi, L., Garnett, C. M., Chiswell, B. and Moore, M. (1999). Tumours in mice induced by exposure to sodium arsenate in drinking water. Third International Conference on Arsenic Exposure and Health Effects, San Diego, CA, United States, 12–15 July 1998. Amsterdam, Netherlands: Elsevier. doi: 10.1016/B978-008043648-7/50025-X
Preprint
Conference Item
Seawright, A. A. (2003). Some Unique Lesions Found in Domestic and laboratory Animals Caused by the Ingestion of Poisonous Plants. The American Society for Veterinary Clinical Pathology, Banff, Canada, 15-19 November 2003. Middleton, USA: American College of Veterinary Pathologists.
Research Report
Shaw, G. R., Stewart, I., Seawright, A. A., Webb, P. M., Sadler, R., Neville, G. R., Eaglesham, G., Schluter, P. J. and Robinson, I. (2001). Research Project on Assessment of Human Dermal Toxicity Related to Recreational Exposure to Blue-Green Algae in SEQWB Controlled Reservoirs. Brisbane, Australia: NRCET.